Participants who simultaneously received the flu and Pfizer vaccine (aOR, 1.08 95% CI, 1.06 to 1.10) or the flu and Moderna vaccine (aOR, 1.11 95% CI, 1.08 to 1.14) were slightly more likely to report a systemic reaction than those who received a COVID-19 booster alone. Of these participants, 59.7% were female, 40.6% were aged 12 to 49 years, 25.8% were 50 to 64, 27.0% were 65 to 74, and 6.6% were 75 or older.Ī total of 58.9% of 61,390 participants who simultaneously received the flu vaccine and the Pfizer/BioNTech COVID-19 booster and 68.6% of 30,633 of those who simultaneously received the flu vaccine and the Moderna booster reported systemic adverse reactions. Of the 981,099 volunteers, 92,023 (9.4%) reported having received simultaneous flu and COVID-19 booster vaccination. Fatigue, headache, muscle aches most reported Authorization of COVID-19 vaccine boosters in the United States coincided with the recommended period for flu vaccination, increasing the odds of simultaneous receipt.
The authors noted that current clinical CDC guidance states that COVID-19 vaccines may be given without regard to timing of other vaccines, including during the same vaccination visit. Volunteers responded to at least one health survey through the CDC's smartphone-based v-safe monitoring system during the study period. In the study, published today in JAMA Network Open, the Centers for Disease Control and Prevention (CDC) COVID-19 Response Team and Emory University analyzed rates of systemic adverse events among 981,099 Americans aged 12 years and older in the week after either simultaneous flu and COVID-19 booster doses or the booster alone from Sep 22, 2021, to May 1, 2022. Self-reported data from nearly 1 million Americans show an 8% to 11% higher rate of mostly mild systemic adverse events after simultaneous seasonal flu vaccine and mRNA COVID-19 booster (third) doses than with the COVID-19 booster alone.
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